300 hypothyroidism symptoms: count how many you have


The World Health Organization estimates that there are 750 million people with thyroid dysfunction worldwide, and The American Thyroid Association writes up to 60 percent of those with thyroid disease are UNAWARE of their condition. While the statistics show that women are more likely to develop thyroid disease, thyroid disease is a condition that affects women, men, and children of all ages.

Of the 750 million people with thyroid dysfunction, 1.2 million of them are currently following my site Hypothyroid Mom (I won’t stop until I find all 750 million). The majority are here because they are still feeling unwell despite standard hypothyroidism treatment. Most are told their thyroid is “fine” while they struggle with a countless number of symptoms. Often times their doctors have no clue the vast array of symptoms that can befall a thyroid patient and most patients have no idea their symptoms could possibly be a red flag that their condition is not being well treated. Some may back down from speaking up to their doctor because they feel “doctor knows best” or that they don’t have any scientific proof to back up their claims…until now.

The first step before anything with hypothyroidism is to know the symptoms. There are over 300. Yes you read that correctly. Every single cell of the body requires thyroid hormone for proper functioning, so every single part of the body is vulnerable when you have abnormal thyroid function.

Knowing the symptoms is more powerful than you can imagine.

Of course not every single symptom you experience is caused by your thyroid. And not everyone will present with the exact same symptoms. It’s an interesting thing really how thyroid disease can present in different ways in different people. However, if you experience a high number of these symptoms overall and you haven’t been given a solid medical reason to explain them all, then you know you may be on to something. It may be your thyroid.

At my lowest point with hypothyroidism when I could barely keep my eyes open through the day, I suffered from 118 symptoms on this list. I was a walking billboard for hypothyroidism, yet my doctor at that time insisted my thyroid was “normal”. Now thanks to optimal thyroid treatment including all the many pieces of the thyroid puzzle that I include at Hypothyroid Mom, which also meant researching the best thyroid doctors on the planet (and I’m blessed to include so many of them as guest writers on my website), the majority of my symptoms have completely disappeared. I just recently counted the number of symptoms that I experience and I only have 15 left that persist but even then most of the 15 are greatly improved. I am over the moon happy about feeling well with hypothyroidism and so thankful.

Now come on, let’s get you well too.

If you are experiencing a high number of the symptoms on this list, then this is your big red flag (and I’m waving it wildly at you) that, one, you have hypothyroidism that hasn’t been diagnosed or, two, you have diagnosed hypothyroidism but it is miserably treated.

More than likely for the first time in the history of your disease, you will see a full list of possible symptoms in front of you and you will probably have close to 100 in total or more symptoms that you had no idea could be related to your thyroid.

When your doctor insists, “Your thyroid is fine.”

Now, you can shoot back, “No it’s not.” And you have proof.

I have spent more days than you can imagine creating this article, carefully putting together a list of scientific studies to back up the symptoms on this list so that you have them at the ready to show your doctor as your proof. There is no way a doctor can swiftly dismiss your concerns when you walk in armed with the comprehensive list of the most recent scientific studies that I’ve listed at the bottom of this article.

Even if your current doctor refuses to help despite this, you will know without a shadow of a doubt that you need to find an open-minded thyroid doctor. Even if that means firing ten doctors until you find the one that helps.

I hope this article above all others at Hypothyroid Mom, passes the power of healing into your hands. Your symptoms are not all in your head. No, you are not crazy or lazy or faking, even if other people make you feel that way. Convincing yourself of this can change your world.

I’ve included at the bottom of each section an area to score yourself. I want you to count how many of the symptoms that I’ve listed for each section that you actually struggle with yourself. At the end, you will be adding up your total score out of 310.

I know this is a seriously long list, but getting that final score may very well shock you and (my great hope) spur you into the biggest wellness journey of your life. Remember to count your symptoms again over time to track your improvements, especially:

  • after you’ve found a new, open-minded thyroid doctor thanks to this list of resources at Hypothyroid Mom
  • or when you feel better since getting comprehensive thyroid lab testing
  • or after investigating some of the effective thyroid treatments in my articles
  • or after trying my top picks of hypothyroidism supplements

You may be wondering how to print this article or any other article at Hypothyroid Mom. Go to the article you wish to print, then select File then Print or type command P. This will open a printing window where you select your settings and print.

Symptoms of Hypothyroidism: Energy & Sleep

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Weight

symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Body Temperature

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Vulnerability to Infections

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Multiple Autoimmune Diseases

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Teeth, Mouth, Throat

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Ears

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Eyes

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Hair

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Legs, Arms, Feet, Hands

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Skin

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Digestion

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Pain

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Menstrual Disorders

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Fertility, Pregnancy & Postpartum

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Brain

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Kidney & Bladder

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Liver & Gallbladder

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Lungs

300 hypothyroidism symptoms: count how many you have


YOUR SCORE: ______

Symptoms of Hypothyroidism: Heart

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Now add up all your individual scores to get your total number of hypothyroidism symptoms out of the 310 listed.

Your Total Hypothyroidism Symptoms Score:

______ / 310

Are you shocked?

I knew you would be.

Hypothyroidism Symptoms in Recent Scientific Literature:

Energy & Sleep

Basoglu, O.K., Tasbakan, M.S. Gender difference in clinical and polysomnographic features of obstructive sleep apnea: a clinical study of 2827 patients. Sleep Breath. 2017 Feb 14.

Chaker, L., et al. Hypothyroidism. Lancet. 2017 Sep 23;390(10101):1550-1562.

Cohen, A., et al. Comorbidities in a community sample of narcolepsy. Sleep Med. 2018 Mar;43:14-18.

Dunn, D., Turner, C. Hypothyroidism in Women. Nurs Womens Health. 2016 Feb-Mar;20(1):93-8.

Misiolek, M., et al. Sleep apnea syndrome and snoring in patients with hypothyroidism with relation to overweight. J Physiol Pharmacol. 2007 Mar;58 Supplements 1:77-85.

Petrone, A., et al. Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment. Sleep Med. 2016 Jul;23:21-25.

Sethi, B., et al. The Thyroid Registry: Clinical and Hormonal Characteristics of Adult Indian Patients with Hypothyroidism. Indian J Endocrine Metab. 2017 Mar-Apr;21(2):302-307.

Louwerens, M. et al. Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism. Our J Endocrine. 2012 Dec;167(6):809-15.


Harbuwono, D.S., et al. Improvement of Metabolic Parameters Resulted from Levothyroxine Therapy in Hypothyroid Type 2 Diabetes Mellitus Patient. Acta Med Indones. 2016 Apr;48(2):145-7.

Laurberg, P., et al. Thyroid Function and Obesity. Eur Thyroid J. 2012 Oct;1(3):159-167.

Mullur, R., et al. Thyroid Hormone Regulation of Metabolism. Physiol Rev. 2014 Apr;94(2):355-382.

Ozair, M., et al. Prevalence of thyroid disorders in North Indian Type 2 diabetic subjects: A cross sectional study. Diabetes Metab Syndr. 2017 Dec 20. pii: S1871-4021(17)30421-6.

Răcătăianu, N., et al. Thyroid disorders in obese patients. Does insulin resistance make a difference? Arch Endocrinol Metab. 2017 Dec;61(6):575-583.

Subekti, I., et al. Thyroid Dysfuntion in Type 2 Diabetes Mellitus Patients. Acta Med Indones. 2017 Oct-49(4):314-323.

Witkowska-Sędek, E., et al. Thyroid dysfunction in obese and overweight children. Endokrynol Pol. 2017;68(1):54-60.

Body Temperature

Obermeyer, Z., et al. Individual differences in normal body temperature: a longitudinal big data analysis of patient records. BMJ. 2017 Dec 13;359:j5468.

Warner, A., et al. Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1. Proc Natl Acad Sci USA. 2013 Oct 1;110(40):16241-6.

Warner, A., Mittag, J. Brown fat and vascular heat dissipation. Adipocyte. 2014 Jul 1; 3(3): 221–223.

Vulnerability to Infections

Günel, C., et al. [The relationship between hypothyroidism and rhinitis]. Kulak Burun Bogaz Ihtis Derg. 2010 Jul-Aug;20(4):163-8.

Khan, Q., et al. Prevalence of Hepatitis B and C infection in autoimmune thyroid patients. Journal of Entomology and Zoology Studies. 2017;5(2):1335-1337.

Nóbrega, M.M., et al. Bacteriuria and urinary tract infection after female urodynamic studies: risk factors and microbiological analysis. Am J Infect Control. 2015 Oc 1;43(10):1035-9.

Ren, H., et al. The non-thyroidal illness syndrome is associated with postoperative surgical site infections in enterocutaneous fistulae. Int J Surg. 2018 Feb 7;51:213-217.

Multiple Autoimmune Diseases

Anoop, J., et al. Unravelling thyroid dysfunction in rheumatoid arthritis: History matters. Int J Rheum Dis. 2018 March;21(3):688-692.

Barmpari, M.E., et al. Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity. J Diabetes Res. 2017;2017:6505814.

Edwards, N.C., et al. Comorbidity in US patients with multiple sclerosis. Patient Relat Outcome Meas. 2018 Feb 13;9:97-102.

Norström, F., at al. The Impact of Thyroid Autoimmunity on Thyroid function in 12-year-old Children with Celiac Disease. J Pediatr Gastroenterol Nutr. 2018 Jan 25.

Solanki, K.K., et al. High Prevalence of Antithyroid Antibodies in a New Zealand Cohort of Patients with Systemic Sclerosis. J Clin Rheumatol. 2018 Feb 15.

Vachiramon, V., et al. Prevalence of Thyroid Abnormalities in Thai Patients with Vitiligo. Biomed Res Int. 2017;2017:7502935.

Teeth, Mouth, Throat

Costa, C., et al. A systemic disease un…suspected by physical examination. BMJ Case Report. 2014 Oct 9;2014.

Dudhia, S.B., Dudhia, B.B. Undetected hypothyroidism: A rare dental diagnosis. J Oral Maxillofac Pathol. 2014 May;18(2):315-9.

Hamdan, A.L., et al. Phonatory symptoms and impact on quality of life in female patients with goiter. Ear Nose Throat J. 2016 Jul;95(7):E5-E10.

Li, D., et al. The Association of Thyroid Disease and Oral Lichen Planus: A Literature Review and Meta-analysis. Front Endocrine (Lausanne). 2017 Nov 9;8:310.

Naik, M.M., Vassandacoumara, V. Qualitative and quantitative salivary changes and subjective oral dryness among patients with thyroid dysfunction. Indian J Dent Res. 2018 Jan-Feb;29(1):16-21.

Simmons, L.H., et al. Case 38-2014: A man with sore throat, hoarseness, fatigue, and dyspnea. N Engl J Med. 2015 Mar 5;372(10):982.

Tong, H.J., et al. Management of a child with severe hypodontia in th mixed dentition stage of development. Our Arch Paediatr Dent. 2014 Dec;15(6):449-54.

Venkatesh Babu, N.S., Patel, P.B. Oral health status of children suffering from thyroid disorders. J Indian Soc Pedod Prev Dent. 2016 Apr-Jun;34(2):139-44.

Wémeau, J.L., et al. [Oral and dental expression of thyroid diseases]. Presse Med. 2017 Sep;46(9):864-868.


Andrade, C.L.O., et al. Mechanisms involved in hearing disorders of thyroid ontogeny: a literature review. Arch Endocrine Metab. 2017 Setp-Oct;61(5):501-505.

Kim, H.J., et al. Analysis of the prevalence and associated risk factors of tinnitus in adults. PLoS One. 2015 May 28;10(5):e0127578.

Messina, A., et al. Italian survey on benign paroxysmal positional vertigo. Acta Otorhinolaryngol Ital. 2017 Aug;37(4):328-335.

Orhan, I., et al. Tympanometric changes and eustachian tube function in patients with hypothyroidism. J Craniofac Surg. 2014 May;25(3):e230-3.

Santosh, U.P., Rao, M.S. Incidence of Hypothyroidism in Meniere’s Disease. J Clin Diagn Res. 2016 May;10(5):MC01-3.

Wojtczak, R., et al. Epidemiology of dizziness in northern Poland – The first Polish neurootologic survey of the general population. Ann Agric Environ Med.2017 Sep 21;24(3):502-506.


Choi, H.Y., et al. Recurrent oculomotor neuritis related to autoimmune hypothyroidism. Case Report. Neuro Endocrinol Lett. 2015;36(4):303-5.

Ju, C., Zhang, L. Diplopia in a patient with Hashimoto’s thyroiditis: A case report and literature review. Medicine (Baltimore). 2017 Jun;96(26):e7330.

Wang, S., et al. Hypothyroidism as a risk factor for open angle glaucoma: A systematic review and meta-analysis. PLoS One. 2017 Oct 25;12(10):e0186634.


Bin Saif, G.A. Severe subtype of alopecia areata is highly associated with thyroid autoimmunity. Saudi Med J. 2016 Jun;37(6):656-61.

Contreras-Jurado, C., et al. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors. PLoS One. 2014;9(9):e108137.

Contreras-Jurado, C., et al. Thyroid hormone signaling controls hair follicle stem cell function. Mol Biol Cell. 2015 Apr 1;26(7):1263-72.

Siah, T.W., et al. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Int J Trichology. 2016 Apr-Jun;8(2):57-61.

Wolff, H., et al. The Diagnosis and Treatment of Hair and Scalp Diseases. Dtsch Arztebl Int. 2016 May 27;113(21):377-86.

Legs, Arms, Feet, Hands

Aishwarya, K., et al. Clinical Signs in Hypothyroidism – Myoedema and Woltman Sign. QJM. 2017 Nov 28.

Bano, A., et al. Gait patterns associated with thyroid function: The Rotterdam Study. Sci Rep. 2016 Dec 14:6:38912

Razi, A., et al. Evaulation of dermal symptoms in hypothyroidism and hyperthyroidism. Pak J Biol Sci. 2013 Jun 1;16(11):541-4.


Al-Arashi, W., et al. [A man who was unable to open his eyes]. Ned Tijdschr Geneeskd. 2018;162(0):D2176.

Firouzi, A., et al. The Combined Effects of Levothyroxine and Low Level Laser therapy on Wound Healing in Hypothyroidism Male Rat Model. J Lasers Med Sci. 2018 Winter;9(1):7-10.

Haritha, S., Kirthi Sampath, K. Skin Manifestations of Hypothyroidism-A Clinical Study. Journal of Dental and Medical Sciences. 2013 May-Jun;7(2):58-60.

Lause, M., et al. Dermatologic manifestations of endocrine disorders. Transl Pediatr. 2017 Oct;6(4):300-312.

Keen, M.A., et al. A Clinical Study of the Cutaneous Manifestations of Hypothyroidism in Kashmir Valley. Indian J Dermatol. 2013 Jul-Aug;58(4):326.

Safer, J.D. Thyroid hormone action on skin. Dermatoendocrinol. 2011 Jul-Sep;3(3):211-215.

Safer, J.D. Thyroid Hormone and Wound Healing. J Thyroid Res. 2013;2013:1234538.

Selvendran, S.S., et al. Chronic urticaria and thyroid autoimmunity: a perplexing association. Oxf Med Case Reports. 2018 Feb 22;2018(2):omx099.

Stewart, T.J., Bazergy, C. Thyroid autoimmunity in female post-adolescent acne: A case-control study. Dermatoendocrinol. 2017 Dec 12;9(1):e1405198.

Takir, M., et al. Skin findings in autoimmune and non autoimmune thyroid disease with respect to thyroid functional status and healthy controls. Turk J Med Sci. 2017 Jun 12;47(3):764-770.


Akyüz, F., Mutluay Soyer, Ö. Which diseases are risk factors for developing gastroesophageal reflux disease? Turk J Gastroenterol. 2017 Dec;28(Supplement 1):S44-S47.

Carter, D., et al. The Severity of Symptoms Related to Irritable Bowel Syndrome is a Risk Factor for the Misclassification of Significant Organic Disease. J Clin Gastroenterol. 2016 June 24.

Chogle, A., Saps, M. Yield and cost of performing screening tests for constipation in children. Can J Gastroenterol. 2013 Dec;27(12):e35-8.

İlhan, M., et al. Esophagus motility in overt hypothyroidism. J Endocrinol Invest. 2014 Jul;37(7):639-44.

Kopylov, U., et al. Obesity, metabolic syndrome and the risk of development of colonic diverticulosis. Digestion. 2012;86(3):201-5.

Mapel, D.W., et al. The epidemiology and treatment of anal fissures in a population-based cohort. BMC Gastroenterol. 2014 Jul 16;14:129.

Shizuma, T. Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review. Biomed Res Int. 2016;2016:5187061.


Brooks, L., et al. Assessing the prevalence of autoimmune, endocrine, gynecologic, and psychiatric comorbidities in an ethnically diverse cohort of female fibromyalgia patients: does the time from hysterectomy provide a clue? J Pain REs. 2015 Aug 20;8:561-9.

Eslamian, F., et al. Electrophysiologic changes in patients with untreated primary hypothyroidism. J Clin Neurophysiol. 2011 Jun;28(3):323-8.

Evans, R.W., Timm, J.S. New Daily Persistent Headache Caused by a Multinodular Goiter and Headaches Associated with Thyroid Disease. Headache. 2017 Feb;57(2):285-289.

Haliloglu, S., et al. Fibromyalgia in patients with thyroid autoimmunity: prevalence and relationship with disease activity. Clin Rheumatol. 2017 Jul;36(7):1617-1621.

Hezarkhani, S., et al. Rheumatologic manifestations in Iranian patients with autoimmune thyroid diseases. J Clin Diagn Res. 2014 Oct;8(10):MC06-8.

Kame, S.S., Bhalerao, N.S. Carpal Tunnel Syndrome in Hypothyroidism. J Clin Diagn Res. 2016 Feb;10(2):OC36-8.

See, L.C., et al. Hyperthyroid and hypothyroid status was strongly associated with gout and weakly associated with hyperuricaemia. PLoS One. 2014 Dec 8;9(12):e114579.

Song, H.S., et al. Association between temporomandibular disorders, chronic diseases, and ophthalmologic and otolaryngology disorders Korean adults: A cross-sectional study. PLoS One. 2018 Jan 31;13(1):e0191336.

Tan, E.K., et al. Restless legs symptoms in thyroid disorders. Parkinsonism Relat Disord. 2004 Mar;10(3):149-51.

Menstrual Disorders

Ajmani, N.S., et al. role of Thyroid Dysfunction in Patients with Menstrual Disorders in Tertiary Care Center of Walled City of Delhi. J Obstet Gynaecol India. 2016 Apr;66(2):115-9.

Digra, M., et al. Thyroid profile in women with menstrual disorders. Int J Reprod Contracept Obstet Gynecol. 2017 Aug;6(8):3300-3305.

Jing, S., et al. Ignored adult primary hypothyroidism presenting chiefly with persistent ovarian cysts: a need for increased awareness. Reprod Biol Endocrinol. 2011;9:119.

Kim, M.H., et al. The relationship between thyroid nodules and uterine fibroids. Endocr J. 2010;57(7):615-21.

Kowalczyk, K., et al. Thyroid disorders in polycystic ovary syndrome. Eur Rev Med Pharmacol Sci. 2017 Jan;21(2):346-360.

Osman, H.A., et al. Precocious puberty: An experience from a major teaching hospital in Central Saudi Arabia. Sudan J Paediatr. 2017;17(1):19-24.

Rajiwade, S.R., et al. Endocrine Abnormalities in Adolescents with Menstrual Disorders. J Obstet Gynaecol India. 2018 Feb;68(1):58-64.

Fertility, Pregnancy & Postpartum

Getahun, D., et al. Association between maternal hypothyroidism and autism spectrum disorders in children. Pediatr Res. 2017 Dec 15.

López-Tinoco, C., et al. Impact of positive thyroid autoimmunity on pregnant women with subclinical hypothyroidism. Endocrinol Diabetes Nutr. 2018 Jan 6.

Martinez, M., et al. Hypothyroidism during pregnancy and its association to perinatal and obstetric morbidity: a review. Endocrinol Diabetes Nutrients. 2018 Feb;65(2):107-113.

Miranda, A., Sousa, N. Maternal hormal milieu influence on fetal brain development. Brain Behav. 2018 Jan 24;8(2):e00920.

Patel, N., Kashanian, J.A. Thyroid Dysfunction and Male Reproductive Physiology. Semin Reprod Med. 2016 Nov;34(6):356-360.

Smith, A., et al. Thyroid disorder in pregnancy and postpartum. Just Prescribed. 2017 Dec;40(6):214-219.

Thompson, W., et al. Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopment disorders in offspring. A systematic review and meta-analysis. Clin Endocrinol (Oxf). 2018 Jan 11.


Calzà, L., et al. Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair. Vitam Horm. 2018;106:253-281.

Dold, M., et al. Clinical correlates of augmentation/combination treatment strategies in major depressive disorder. Acta Psychiatr Scand. 2018 Feb 28.

Nazou, M., et al. [Psychotic episode due to Hashimoto’s thyroiditis]. Psychiatriki.2016 Apr-Jun;27(2):144-7.

Pandey, V.P., et al. Verbal Episodic Memory in Young Hypothyroid Patients. Indian J Endocrine Metab. 2017 Nov-Dec;21(6):812-814.

Parikh, N., et al. A case report on myxedema madness: curable psychosis. Indian J Psychol Med. 2014 Jan;36(1):80-1.

Sierra, P., et al. What is the real significance and management of major thyroid disorders in bipolar patients? Rev Psiquiatr Salud Ment. 2014 Apr-Jun;7(2):88-95.

Szlejf, C., et al. Thyrotropin level and cognitive performance: Baseline results from the ELSA-Brasil Study. Psychoneuroendocrinology. 2018 Jan;87:152-158

Tayde, P.S., et al. Hypothyroidism and Depression: Are Cytokines the Link? Indian J Endocrine Metab. 2017 Nov-Dec;21(6):886-892.

Ueno, S., et al. Acute psychosis as an initial manifestation of hypothyroidism: a case report. J Med Case Rep. 2015 Nov 17;9:264.

Kidneys & Bladder

Chang, Y.C., et al. Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study. Sci Rep. 2018 Feb 1;8(1):2031.

Cuna, V., et al. Functional Abnormalities and Thyroid Nodules in Patients with End-stage Renal Disease. In Vivo. 2017 Nov-Dec;31(6):1203-1208.

Da Costa, A.B., et al. High prevalence of subclinical hypothyroidism and nodular thyroid disease in patients on hemodialysis. Hemodial Int. 2016 Jan;20(1):31-7.

Justo, D., et al. Asymptomatic urinary retention in elderly women upon admission to the Internal Medicine department: A prospective study. Neurourol Urodyn. 2017 Mar;36(3):794-797.

Keller, J.J., et al. Comorbidities of bladder pain syndrome/interstitial cystitis: a population-based study. BJU Int. 2012 Dec;110(11 Pt C):E903-9.

Patil, V.P., et al. Evaluation of renal function in subclinical hypothyroidism. J Lab Physicians. 2018 Jan -Mar;10(1):50-55.

Uemura, O., et al. Influence of thyroid function ion glomerular filtration rate and other estimates of kidney function in two pediatric patients. CEN Case Rep. 2018 Feb 28.

Liver & Gallbladder

Duong, N., et al. Case of acute mixed liver injury due to hypothyroidism. BMJ Case Rep. 2018 Jan 23;2018.

He, W., et al. Relationship between Hypothyroidism and Non-Alcoholic Fatty Liver Disease: A Systemic Review and Meta-analysis. Front Endocrine (Lausanne). 2017 Nov 29;8:335.

Laukkharinen, J., et al. The underlying mechanisms: how hypothyroidism affects the formation of common bile duct stones-a review. HPB Surg. 2012;2012:102825.

Oh, R.C., et al. Mildly Elevated Liver Transaminase Levels: Causes and Evaluation. Am Fam Physician. 2017 Dec 1;96(11):709-715.

Rodriguez Lugo, D.A., et al. [Primary biliary cholangitis. Part 1. State of the art, epidemiology, physiopathology and clinical manifestations]. Rev. Gastroenterol Peru. 2017 Oct-Dec;37(4):357-364.

Shabanzadeh, D.M., et al. Screen-detected gallstone disease and autoimmune diseases – A cohort study. Dig Liver Dis. 2018 Jan 31. pii: S1590-8658(18)30141-5.

Sinha, R.A., et al. Direct effects of thyroid hormones on hepatic lipid metabolism. Nat Rev Endocrine. 2018 Feb 23.


Al-Sofiani, M., et al. Hypothyroidism and non-cardiogenic pulmonary edema: are we missing something here? Endocrinol Diabetes Metab Case Rep. 2015;2015:150014.

Condruta, L., et al. Respiratory manifestations in endocrine diseases. Clujul Med. 2016;89(4):459-463.

Fan, Y.M., et al. Prognostic factors for treatment success in patients with multidrug-resistant tuberculosis in China. Int J Tuberc Lung Dis. 2018 Mar 1;22(3):300-305.

Glyn, T., et al. Lessons learnt from a case of missed central hypothyroidism. Endocrinol Diabetes Metab Case Rep. 2017 Dec 2;2017.

Lencu, C., et al. Respiratory manifestations in endocrine diseases. Clujul Med.2016;89(4):459-463.

Leonardi, A., et al. Pericardial Effusion as a Presenting Symptom of Hashimoto Thyroiditis: A Case Report. Int J Environ Res Public Health. 2017 Dec 14;14(12).pii

Munehisa, F., et al. Respiratory failure associated with hypoventilation in a patient with severe hypothyroidism. Respirol Case Rep. 2014 Jun;2(2):79-80.

Nafae, R.M., et al. Thyroid function in respiratory failure patients. Egyptian Journal of Chest Diseases and Tuberculosis. 2014 Apr;63(2):513-521.

Papaioannou, O., et al. Metabolic Disorders in Chronic Lung Diseases. Front Med (Lausanne). 2018 Jan 18;4:246.

Sadek, S.H. Pulmonary consequences of hypothyroidism. Ann Thorac Med. 2017 Jul-Sep;12(3):204-208.

Sorensen, J.R., et al. Respiratory Manifestations of Hypothyroidism: A Systematic Review. Thyroid. 2016 Nov;26(11):1519-1527.

Ulasli, S.S., et al. Effect of thyroid function on COPD exacerbation frequency: a preliminary study. Multidiscip Respir Med. 2017 Dec 14;14(12). pii: E1576.


Altamirano Ufion, A., et al. Subclinical Hypothyoridism and Its Association with Increased Cardiovascular Mortality. Cardiol Res Pract. 22017;2017:7539735.

Bano, A., et al. Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality: The Rotterdam Study. Circ Res. 2017 Dec 8;121(12):1392-1400.

Beukhof, C.M., et al. Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids. Thyroid. 2018 Feb;28(2):168-174.

Binu, A.J., et al. The Heart of the Matter: Cardiac Manifestations of Endocrine Diseases. Indian J Endocrine Metab. 2017 Nov-Dec;21(6):919-925.

Charles, L., et al. Secondary Hypertension: Discovering the Underlying Cause. Am Fam Physician. 2017 Oct 1;96(7):453-461.

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